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Many patients tolerate an adjustment period where nausea and mild bloating occur but resolve as the body adapts

DSIP dosing protocols require careful titration and timing improvement to achieve therapeutic benefits while minimizing side effects

Standard FDA review under PDUFA takes approximately 12 months from NDA submission

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1557 In preclinical or animal models, hyperglycemia can impact oocyte competence by known and unknown mechanisms

Consequently, the impaired removal of cellular waste perpetuates chronic inflammation, fostering a vicious cycle that fuels MASH pathology [39]