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Centimillionaire longevity guru Bryan Johnson took 5-MeO-DMT, a powerful psychedelic, on livestream part of his quest to live forever.

A phase 3 trial found the once-daily pill orforglipron lowered blood sugar and body weight more than oral semaglutide in adults with type 2 diabetes.

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We conducted a comprehensive literature search using databases including Scopus, Google Scholar, PubMed, and the Cochrane Library to identify clinical, in-vivo, and in-vitro studies focusing on the diverse effects of GLP-1 receptor agonists

Carmot Therapeutics has revealed preliminary data from the single ascending dose (SAD) portion of its ongoing Phase 1 clinical trial for CT-996, an oral small molecule GLP-1 receptor agonist (RA) currently being evaluated in a first-in-human clinical trial in participants with obesity or overweight.CT-996 is a once-daily oral, small molecule GLP-1 receptor agonist being developed for the treatment of obesity and type 2 diabetes (T2D)