glp-1 receptor agonists for individualized treatment of type 2 diabetes mellitus Possible mechanisms of action of

Zepbound and Mounjaro use the same active ingredient tirzepatide, similar to semaglutide, FDA-approved for people with obesity or overweight accompanied by diet and fitness

YW: Writing review & editing, Writing original draft

found that the protective effect of dulaglutide on learning and memory impairment might be the result of reducing the hyperphosphorylation of tau and neurofilament proteins in a PI3K/AKT/GSK3 signaling pathway-dependent manner (48)

Inhibitors of the peptidomimetic class such as saxagliptin and vildagliptin mimic the dipeptide terminal of DPP4 at the cleavage site of the incretin hormone substrates

The other has to do with reducing inflammation

Allan KC, et al