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In pharmacovigilance databases, anxiety comprised 38.7% of psychiatric adverse event reports, but psychiatric reports as a whole represented only 1.18% of total adverse event reports for GLP-1 receptor agonists

GLP-1 side effects include gastrointestinal complications, such as nausea, vomiting, diarrhea, constipation, and diverticulitis

It is reported that ARR1 controls the desensitization of the GLP-1R

In the US, it is primarily used for the treatment of postmenopausal women with osteoporosis at high risk of fracture and for treatment to increase bone mass in men with osteoporosis at high risk of fracture

There are very few concerns about serious long term side effects in people with type 2 diabetes or obesity, he said

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