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The first four weeks at 0.25 mg produce the mildest side effects

However, these observations need to be confirmed by future trials [138]

Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: The STEP 4 randomized clinical trial

Because of this and because we were the first to describe DPP4 as a novel adipokine linked to parameters of the metabolic syndrome (4), we decided to develop an adipose tissue-specific KO mouse model
