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Unopened Wegovy can tolerate room temperature (46 to 86 degrees Fahrenheit) for up to 28 days, but this should be treated as a backup window, not a storage strategy

Circulating sDPP-4 is increased in obesity and insulin resistance but is not related to systemic metabolic inflammation

25 Given concerns that skeletal muscle loss may predispose patients to long-term metabolic complications, including sarcopenia, it is recommended that individuals undergoing treatment with GLP-1 RAs receive adequate protein intake and appropriate micronutrient supplementation to preserve muscle mass and function, thereby maximizing the clinical benefits of therapy

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