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The SOS study reported a decrease in CV events and CV mortality in patients undergoing BS as compared to control group [49]

Increased beta-cell function and insulin biosynthesis has been demonstrated for both liraglutide and semaglutide, with favorable proinsulin/insulin ratios compared with other glucose-lowering agents (124, 141, 143, 152155)

MOTS-C addresses mitochondrial function, not appetite they work on completely different pathways

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What are the biological factors that contribute to weight gain