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While incretin-based therapies have been commercially available since 2005, most clinical trials only report short term outcomes

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The 2026 review is blunt that diet is secondary, noting these measures are substantially less effective if dose titration is not actively and thoughtfully managed

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But Mounjaro, which was approved five years after Ozempic and whose chemical name is tirzepatide, acts on both GLP-1 and GIP receptors