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Still, while the new combinations would be great for people who need to lose more weight, Korner said, not everyone needs the so-called big gun. Drugs like retatrutide may be most appropriate for someone who has a body mass index above 45 above 30 is considered obese and for whom existing drugs havent worked sufficiently, Dushay said

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Understanding the Results The calculator displays mean weight loss percentages, which represent the average percent change in body weight from baseline for each trial arm