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Although the therapeutic implications of the lipogenic actions of GIP are debated, its ability to improve lipid and glucose metabolism is especially evident when paired with the anorexigenic mechanism of GLP-1

For patients with significant insulin resistance, type 2 diabetes, or metabolic syndrome, the dual-action mechanism often delivers noticeably stronger results

Some individuals may also compensate for reduced appetite at meals by increasing snacking or consuming caloric beverages

It remains investigational

10.1111/all.12350 8 FriasJ

Hui H, Farilla L, Merkel P, Perfetti R (2002) The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects