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Un estudio adicional que incluy 1,201 pacientes, se realiz para comparar la eficacia y seguridad de Ozempic 0.5 mg y 1 mg una vez por semana versus dulaglutida 0.75 y 1.5 mg una vez por semana, respectivamente

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CV cardiovascular, GI gastrointestinal, RE extended-release, SC subcutaneous administration The + and symbols indicate the efficacy profile or adverse effect profile of each parameter, with more symbols meaning greater strength or severity

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Mechanism In response to a previous FDA inquiry, two short-term mechanical studies were conducted using exenatide and liraglutide in a diabetic rat model, wherein one rat administered with exenatide died of pancreatic necrosis, while the others exhibited acinar-to-ductal metaplasia and ductal hyperplasia, indicative of potential premalignant alterations [62,63]

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