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N Engl J Med 2007;357(10):10091017

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The Renegade Research Roundtable THE GIST Were back, focusing on GLP-1-enhancing drugs

A landmark study of 120,000 patients found that improving cardiorespiratory fitness from low to above average reduced mortality risk by 40%equivalent to quitting smoking

It remains an investigational drug , which means it is available only for clinical trials and research purposes

Common pathophysiological features exist between T2DM, AD, and PD, including oxidative stress, inflammation, insulin resistance, abnormal protein processing, and cognitive decline, and suggest that effective drugs for T2DM that positively impact the gutbrain axis could provide an effective treatment option for neurodegenerative diseases