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An insulin syringe uses a U-100 scale where 100 units equals 1mL

Dehydration risk: Both medications can increase fluid lossMounjaro through reduced oral intake (due to appetite suppression and nausea) and potential diarrhoea, and magnesium citrate through its osmotic laxative effect

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Since tirzepatide already activates the GLP-1 receptor along with the GIP receptor, combining it with semaglutide could overstimulate these pathways

The use of Tirzepatide can affect metabolic processes by altering diet and calorie intake

However, tirzepatides superior weight loss and glycaemic control in 72-week studies suggest it may ultimately demonstrate strong metabolic benefits across multiple organ systems as longer-term data emerge [10]