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Real-time measurements of dopamine via fiber photometry revealed specific dopamine changes in the nucleus accumbens at both the beginning and end of running bouts, with SG-treated animals showing amplified dopamine dynamics at these key behavioral timepoints

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The results prompt safety concerns for GLP-1RAs, especially with high dose administration, regarding gastrointestinal adverse events

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reducing reliance on costly imports." Key findings: With 98 GLP-1 drugs in trials, patent expiry in 2026 enabling biosimilars, and a projected $150B market by 2035, China could challenge Western dominancedespite regulatory hurdles and US tariffs