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doi: 10.1001/jamainternmed.2025.1794, PMID: [DOI] [PubMed] [Google Scholar] 54

Work in the Trapp laboratory is supported by the Medical Research Council (MRC) (MR/N02589X/1), the National Institutes of Health (NIH) and the European Foundation for the Study of Diabetes (EFSD)

SGLT2 inhibitors are now authorised for the treatment of chronic kidney disease and heart failure in individuals with or without T2DM [1, 2]
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The studies conducted by Mansur et al 23 and Li et al 22 and their respective findings on liraglutides effect on cognitive function are promising, as they observed improvements in cognitive scores and memory, along with enhanced brain activation, indicating the potential neurocognitive benefits of GLP-1 agonists
The outcome? Reduced hunger, effortless smaller portion sizes, and a metabolism optimized to burn calories faster