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The expressed GST genes are distributed across various classes, with a particularly strong representation of the theta class ( GSTT3, n = 41 , Supplementary Dataset 1 )

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Collectively, multifunctional metabolic enzymes act as pivotal hubs linking metabolic reprogramming to therapeutic resistance, serving as upstream initiators of signaling cascades that drive drug tolerance in CRC

Biosynthesis and Accumulation of a Medicinal Compound, Picroside-I, in Cultures of Picrorhiza Kurroa Royle Ex Benth