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For athletes, whose nervous systems are often running hot from training stress, GABA helps bridge the gap between "go mode" and actual restful sleep

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Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome

NAION, non-arteritic anterior ischemic optic neuropathy

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Interestingly, non-pharmacological interventions such as physical exercise (PE) demonstrate protective effects by targeting this pathway in microglia