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Devices for Nasal Administration The deposition of drugs administered in the nasal epithelium plays a crucial role in influencing the nose-to-brain pathway, making it vital to maximize drug deposition on the olfactory epithelium for successful treatment efficacy

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However, no significant difference was recorded in serum levels of bicarbonate, sodium, uric acid, or total protein in the treated group (TG) compared with the positive control (PC) ( Figure 1 )

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