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To further assess the local retention ability of IL/aC@RBAH, we introduced a near-infrared (NIR) fluorescent probe Cypate and intratumorally injected the mixture of Cypate-labeled IL-12 and aCTLA-4 (IL-Cp&aC), IL-Cp/aC@RBC, or IL-Cp/aC@RBAH into the tumors of orthotopic 4T1 tumor-bearing mice for real-time monitoring in situ retention via whole-animal in vivo fluorescence imaging system (IVIS)

J.Jandeleit-DahmK.SzyndralewiezC.TrkN

PSII, photosystem II

doi: 10.7759/cureus.52153

Q., Aqil, A., Kirby, A

But heres the inconvenient truth that the peptide salesmen wont mention: the history of medicine is littered with compounds that worked brilliantly in rodents and failed spectacularly in humans