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But it is a data gap that has never been filled

NAD+ powers energy production and recovery

Women in midlife are already navigating hormonal shifts, underlying conditions, and existing prescription medicationsall of which could influence individual safety concerns and side effects

7.4 Limitations of current therapeutic interventions While therapeutic interventions targeting the gut-brain-metabolic axis, such as probiotics, prebiotics, dietary modifications, and FMT (Contarino et al., 2023), show promise in regulating insulin resistance and cognitive function, several limitations and unresolved issues warrant attention: 7.4.1 Variability in individual response One of the significant challenges is the variability in individual responses to these interventions (Almeida et al., 2022)