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All authors had full access to study data, contributed to the drafting and revision of the manuscript and approved the manuscript for submission

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Injecting too quickly, using cold medication straight from the refrigerator, or repeatedly injecting into the same spot all increase the likelihood of nodule formation

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Advantage: Potential for higher bioavailability than standard oral ingestion Challenge: Peptides are poorly absorbed through intact mucosal membranes without transport mechanisms Evidence: No studies confirm enhanced sublingual bioavailability for Dihexa Standard oral (swallowed): Tablets swallowed with water, absorbed through the gastrointestinal tract

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