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Musculoskeletal recovery claims rest on animal data and anecdote and should be read as hypotheses

doi: 10.1016/j.ccr.2011.01.038 42 YaeTTsuchihashiKIshimotoTMotoharaTYoshikawaMYoshidaGJet al

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For example, in SOD1 G93A -mutant mice, elevated concentrations of Cu have been observed at the presymptomatic stage in skeletal muscle and the spinal cord, and this condition aggravates further during disease progression

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This is achieved through the promotion of NADH oxidation and inhibition of mitochondrial permeability transition, both of which are crucial factors for maintaining cellular energy and survival [19]