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Testosterone replacement therapy (TRT) can help restore optimal testosterone levels to combat these effects

But it does reshape how we think about it: Not just a liver drug Not just a gut effect Potentially a central metabolic regulator And a note of caution: These findings are largely preclinical

This might make the treatment less effective and increase the risk of cancer coming back

Patients with Gastrointestinal Disorders People with Crohns disease or celiac disease have trouble absorbing B12

Proton pump inhibitors and H2-receptor-blocking agents have been implicated as causes or contributors to vitamin B12 deficiency because they can produce iatrogenic gastric achlorhydria (116