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Description
Dihexa, with its combined N-hexanoic-Tyr-Ile-(6) aminohexanoic amide structure, exhibited a significantly extended half-life of 335.5 9.5 min, confirming that both N- and C-terminal modifications are effective strategies for improving metabolic stability [1]

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Liu Y, Xu LP, Dai W, Dong H, Wen Y, Zhang X

Cancer Res 66:37373746 Valis K, Prochazka L, Boura E, Chladova J, Obsil T, Rohlena J, Truksa J, Dong LF, Ralph SJ, Neuzil J (2011) Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner

10.3945/ajcn.111.013441 13 CoelhoD.KimJ
Animals were tested every other day
