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CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome

Preclinical doseresponse immunomodulatory research records hormetic doseresponse of numerous phytochemicals: low/moderate dosage can trigger adaptive cytoprotection but higher or chronic dose can cause counterintuitive effect (e.g

Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis

Chromium has been shown to alter the levels of H3K27Me3, H3K4Me3, and H3K9Me3, which epigenetically modify the DNA packaging of the protein histone H3, indicating trimethylation at the 27th, 4th, and 9th lysine residues of the histone H3 protein, respectively (Sun et al

McCluskey SV, Vu N, Rueter J

doi: 10.1002/mrm.1213