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Chronic hypoxia is common in life and includes environmental hypoxia, such as altitude exposure, and hypoxia of the body or organs during aging and disease [21]

Nature Reviews Rheumatology 10 (1), 4456

Expression of M1 and M2 type-related markers in arterial macrophages after knockdown of RBM15 in the SD rat model of AD was examined by flow cytometry

The mapping, as well as the calculation of the percentages of methylation of cytosines in CG context were performed with the Bismark software ( CCL3 functional annotations, such as transcription start site, single nucleotide polymorphisms and predicted transcription factor binding sites were identified with the UCSC Genome Browser ( Statistical analysis Statistical analyses were performed using GraphPad Prism software (version 8.0.2) (GraphPad Software Inc., Irvine, CA)