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In a study on plant sorghum, the Ka/Ks ratios of these two domains suggested that both domains were under differential selective pressures and the GST_C domain might have been exposed to more relaxed functional constraints (Chi et al
Recent studies have established the carbohydrate response element-binding protein (ChREBP) as essential in this process (192)

CREB, cAMP-response element binding protein

Studies have shown that Liuwei Dihuang Pill (decoction) combined with metformin for the treatment of T2DM may reduce the adverse effects of metformin (Zhao et al., 2019)

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Koruk M., Taysi S., Savas M.C., Yilmaz O., Akcay F., Karakok M

10.1016/j.coi.2020.01.008 187 PardiN.LaBrancheC
