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Cuminum cyminum ameliorates urotoxic effects of cyclophosphamide by modulating antioxidant, inflammatory cytokines, and urinary bladder overactivity: in vivo and in silico investigations

For example, dysregulated IGF signaling is thought to contribute to an imbalance between cancer stem-cell self-renewal and differentiation, resulting in the development of non-differentiated cells with stem cell-like properties, and subsequent malignant transformation [29]

Chiarugi, P., Cirri, P., Raugei, G., Manao, G., Taddei, L

Holmgren, Arne (1997)

Blood Cancer 66:e27954

These are designed to dissolve in the mouth and absorb through the oral mucosa, similar to sublingual drops but in solid form