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These findings elucidate a novel MFAP2-ITGB8-FAK-ERK1/2-ETS2-CYP27A1-LXR signaling axis, significantly activated by CAFs-derived MFAP2 in both in vitro and in vivo models, contributing to immune exhaustion and tumor progression

Neuronal vulnerability and multilineage diversity in multiple sclerosis
Laboratory applications explore the development of combination approaches that target multiple senescence mechanisms simultaneously, while research into biomarkers of senescent cell burden and senolytic administration efficacy enables better experimental monitoring and outcome assessment

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(2013) Epitopes of microbial and human heat shock protein 60 and their recognition in myalgic encephalomyelitis

[DOI] [PubMed] [Google Scholar] Nagy L