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doi: 10.1016/0014-5793(70)80521-X

Eli Lilly said that obesity increases the risk of diabetes and many metabolic diseases, so treating obesity can improve people's health by reducing the chance of developing metabolic diseases and related complications

It is also important to consider that the identification of cell types responsible for Fc-dependent antibody-mediated protection in mice (and other animal models) does not necessarily translate directly to humans owing to factors including differences in the FcR expression profile of these cells (Table 1) and differences in the relative abundance of these cell types in tissues and in circulation

Originally containing the important cytosolic CXC motif, CD4 then underwent rapid evolution at two distinct protein-protein interaction sites in D1 and D2, both bearing important Cys residues

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By 2014 the two scientists had managed to achieve their goal