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IGF-1 stimulates both the proliferation and differentiation of skeletal muscle satellite cells, leading to significant increases in muscle fiber size. Florini et al., Endocrine Reviews 2

An API is said to be biologically available (bioavailable) when it enters the blood stream

Depending on the area treated, other parts of your skin may be covered
Claudin-1, -2 and -3 are selectively expressed in the epithelia of the choroid plexus of the mouse from early development and into adulthood while claudin-5 is restricted to endothelial cells

Karobath, M., Daz, J
