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The ephrin pathway plays a crucial role in immune function and inflammatory responses and proteomics studies further support evidence of chronic inflammation, perhaps chronic infection (Milivojevic et al., 2020) and immune dysregulation (Giloteaux et al., 2023), with additional links to coagulation abnormalities and chronic infection (Nunes et al., 2022)

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doi: 10.1016/j.bcp.2005.07.001

In the research context the molecule also appears in combination protocols for tendons and joints together with BPC-157 and TB-500