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Drug-induced acute liver failure is a fatal disease thats caused by the toxic metabolite N-acetyl-p-benzoquinone-imine that leads to glutathione depletion

Heart rate : Modest increases in resting heart rate were observed in Phase 2 trials

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One day after seeding, media containing drug treatments was added to each well and plates were placed in an Incucyte S3 live-cell imaging system within an incubator maintained at 37C with 5% CO 2