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These components are considered immunological distractors with pro-inflammatory activity, capable of causing dysbiosis and increased intestinal permeability (the so-called leaky gut syndrome), so favoring the development of autoimmune diseases [142]

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At least one effective method of contraception (preferably a user independent form such as intra-uterine device or implant) or two complementary forms of contraception including a barrier method be used

[DOI] [PubMed] [Google Scholar] 44.Balzano T., Forteza J., Borreda I., Molina P., Giner J., Leone P., Urios A., Montoliu C., Felipo V

Each syndrome can be distinguished by its pathophysiologic, therapeutic, and prognostic features