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Although this was an open-label study, without a placebo control group, and as such has some limitations, the study results were able to demonstrate that taking ALA was linked to lower triglycerides, fewer neuropathic symptoms, and a better quality of life

Glutamate Oxidation in Astrocytes: Roles of Glutamate Dehydrogenase and Aminotransferases. Journal of Neuroscience Research 94: 15611571

Mean and standard error of the mean (SEM) pooled from three independent experiments is shown (n = 30)

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In an experimental rat model using endosulfan to cause testicular toxicity, endosulfan has appeared to induce oxidative stress and apoptosis, as demonstrated by increased H2O2 levels, lipid accumulation and reduced activity of anti-oxidant enzymes (SOD, CAT, GPx), as well as altered reduced GSH content and mitochondrial cytochrome c release (275)