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PGC-1 knockdown downregulated MOTS-c protein and mRNA expression in C2C12 myotubes, whereas PGC-1 overexpression upregulated both the protein and mRNA expression of MOTS-c in C2C12 myotubes [57]
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One major limitation is the difficulty in sourcing high-quality and standardized CBD for research purposes, which hinders replication and consistency across studies
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Combining peptide therapy with a healthy lifestyle, including a balanced diet and regular exercise, can enhance results and promote long-term success
